263 lines
10 KiB
C#
263 lines
10 KiB
C#
using FluentAssertions;
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using Microsoft.EntityFrameworkCore;
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using Microsoft.Extensions.DependencyInjection;
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using Microsoft.Extensions.Logging;
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using StackExchange.Redis;
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[Collection("Integration")]
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public class SepsisBundleTests : IAsyncLifetime
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{
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private readonly ApiFixture _fixture;
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private Guid _encounterId;
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private Guid _patientId;
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public SepsisBundleTests(ApiFixture fixture) => _fixture = fixture;
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public async Task InitializeAsync()
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{
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using var scope = _fixture.Services.CreateScope();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await DbResetHelper.ResetAsync(db);
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var patient = new Patient
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{
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Id = Guid.NewGuid(), Mrn = "MRN-BUNDLE-001", FirstName = "Bundle", LastName = "Test",
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DateOfBirth = new DateOnly(1965, 3, 15), Gender = "F",
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CreatedAt = DateTimeOffset.UtcNow
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};
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var encounter = new Encounter
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{
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Id = Guid.NewGuid(), PatientId = patient.Id, EncounterType = EncounterType.Inpatient,
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Status = EncounterStatus.Active, Department = Department.Icu,
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AttendingPhysician = "Dr. Bundle", AdmittedAt = DateTimeOffset.UtcNow,
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CreatedAt = DateTimeOffset.UtcNow
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};
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db.Patients.Add(patient);
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db.Encounters.Add(encounter);
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await db.SaveChangesAsync();
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_patientId = patient.Id;
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_encounterId = encounter.Id;
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var redis = scope.ServiceProvider.GetRequiredService<IConnectionMultiplexer>();
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var cache = redis.GetDatabase();
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foreach (var key in QsofaCalculator.AllCriterionKeys(_encounterId))
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await cache.KeyDeleteAsync(key);
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}
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public Task DisposeAsync() => Task.CompletedTask;
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private async Task CreateSofaSepsisBundleAsync(IServiceScope scope)
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{
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var handler = scope.ServiceProvider.GetRequiredService<SepsisAlertHandler>();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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var alertId = Guid.NewGuid();
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db.ClinicalAlerts.Add(new ClinicalAlert
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{
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Id = alertId,
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EncounterId = _encounterId,
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PatientId = _patientId,
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AlertType = AlertType.SofaSepsis,
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Severity = AlertSeverity.Critical,
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Details = "SOFA delta +2",
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Status = AlertStatus.Open,
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TriggeredAt = DateTimeOffset.UtcNow
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});
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await db.SaveChangesAsync();
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await handler.OnSepsisAlertCreatedAsync(
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_encounterId, alertId, AlertType.SofaSepsis, CancellationToken.None);
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}
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[Fact]
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public async Task SofaSepsisAlert_CreatesBundleWithFourOrders()
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{
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using var scope = _fixture.Services.CreateScope();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await CreateSofaSepsisBundleAsync(scope);
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var bundle = await db.SepsisBundles
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.Include(b => b.Elements)
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.SingleAsync(b => b.EncounterId == _encounterId);
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bundle.ComplianceStatus.Should().Be(SepsisBundleComplianceStatus.InProgress);
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bundle.TriggeringAlertType.Should().Be("SOFA_SEPSIS");
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bundle.DeadlineAt.Should().BeCloseTo(bundle.RecognizedAt.AddHours(1), TimeSpan.FromSeconds(5));
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bundle.Elements.Should().HaveCount(4);
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var orders = await db.Orders
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.Where(o => o.EncounterId == _encounterId)
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.ToListAsync();
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orders.Should().HaveCount(4);
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orders.Should().AllSatisfy(o =>
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{
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o.Status.Should().Be(OrderStatus.Pending);
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o.Description.Should().StartWith("SEP-1:");
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o.OrderedBy.Should().Be("sepsis-bundle-engine");
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});
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var bundleOutbox = await db.OutboxEvents
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.Where(e => e.Topic == "sepsis.bundle.created")
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.SingleAsync();
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bundleOutbox.PartitionKey.Should().Be(_encounterId.ToString());
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}
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[Fact]
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public async Task QsofaScreen_DoesNotTriggerBundle()
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{
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using var scope = _fixture.Services.CreateScope();
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var detector = scope.ServiceProvider.GetRequiredService<QsofaDetector>();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await detector.ProcessObservationAsync(_encounterId, _patientId, "RESP_RATE", 24m);
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await detector.ProcessObservationAsync(_encounterId, _patientId, "SYSTOLIC_BP", 95m);
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(await db.SepsisBundles.CountAsync()).Should().Be(0);
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}
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[Fact]
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public async Task SecondAlert_IdempotentBundle()
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{
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using var scope = _fixture.Services.CreateScope();
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var handler = scope.ServiceProvider.GetRequiredService<SepsisAlertHandler>();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await CreateSofaSepsisBundleAsync(scope);
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var bundleCountAfterFirst = await db.SepsisBundles.CountAsync(b => b.EncounterId == _encounterId);
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bundleCountAfterFirst.Should().Be(1);
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var secondAlertId = Guid.NewGuid();
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db.ClinicalAlerts.Add(new ClinicalAlert
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{
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Id = secondAlertId,
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EncounterId = _encounterId,
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PatientId = _patientId,
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AlertType = AlertType.SofaSepsis,
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Severity = AlertSeverity.Critical,
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Details = "SOFA delta +3",
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Status = AlertStatus.Open,
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TriggeredAt = DateTimeOffset.UtcNow
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});
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await db.SaveChangesAsync();
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await handler.OnSepsisAlertCreatedAsync(
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_encounterId, secondAlertId, AlertType.SofaSepsis, CancellationToken.None);
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var bundleCount = await db.SepsisBundles.CountAsync(b => b.EncounterId == _encounterId);
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bundleCount.Should().Be(1, "a second bundle must not be created while one is IN_PROGRESS");
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var orderCount = await db.Orders.CountAsync(o => o.EncounterId == _encounterId);
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orderCount.Should().Be(4, "no additional orders should be created for the duplicate bundle attempt");
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}
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[Fact]
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public async Task OrderResulted_CompletesElement()
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{
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using var scope = _fixture.Services.CreateScope();
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var bundleService = scope.ServiceProvider.GetRequiredService<ISepsisBundleService>();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await CreateSofaSepsisBundleAsync(scope);
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var lactateElement = await db.SepsisBundleElements
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.Include(e => e.Order)
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.SingleAsync(e => e.ElementType == SepsisBundleElementType.SerumLactate);
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await bundleService.OnOrderResultedAsync(lactateElement.OrderId!.Value);
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var updated = await db.SepsisBundleElements
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.AsNoTracking()
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.SingleAsync(e => e.Id == lactateElement.Id);
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updated.Status.Should().Be(SepsisBundleElementStatus.Completed);
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updated.CompletedAt.Should().NotBeNull();
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var bundle = await db.SepsisBundles.AsNoTracking().SingleAsync();
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bundle.ComplianceStatus.Should().Be(SepsisBundleComplianceStatus.InProgress,
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"bundle should remain in progress until all 4 elements are completed");
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}
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[Fact]
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public async Task AllElementsResulted_BundleCompliant()
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{
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using var scope = _fixture.Services.CreateScope();
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var bundleService = scope.ServiceProvider.GetRequiredService<ISepsisBundleService>();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await CreateSofaSepsisBundleAsync(scope);
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var elements = await db.SepsisBundleElements.ToListAsync();
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foreach (var element in elements)
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await bundleService.OnOrderResultedAsync(element.OrderId!.Value);
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var bundle = await db.SepsisBundles.AsNoTracking().SingleAsync();
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bundle.ComplianceStatus.Should().Be(SepsisBundleComplianceStatus.Compliant);
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bundle.CompletedAt.Should().NotBeNull();
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bundle.CompletedAt.Should().BeBefore(bundle.DeadlineAt,
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"all elements completed within the 1-hour window");
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var outboxEvents = await db.OutboxEvents
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.Where(e => e.Topic == "sepsis.bundle.updated")
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.ToListAsync();
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outboxEvents.Should().HaveCount(4, "one outbox event per element completion");
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}
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[Fact]
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public async Task DeadlinePassed_CompletionMarksNonCompliant()
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{
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using var scope = _fixture.Services.CreateScope();
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var bundleService = scope.ServiceProvider.GetRequiredService<ISepsisBundleService>();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await CreateSofaSepsisBundleAsync(scope);
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var bundle = await db.SepsisBundles.SingleAsync();
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bundle.DeadlineAt = DateTimeOffset.UtcNow.AddHours(-1);
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await db.SaveChangesAsync();
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var elements = await db.SepsisBundleElements.ToListAsync();
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foreach (var element in elements)
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await bundleService.OnOrderResultedAsync(element.OrderId!.Value);
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var updated = await db.SepsisBundles.AsNoTracking().SingleAsync();
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updated.ComplianceStatus.Should().Be(SepsisBundleComplianceStatus.NonCompliant);
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updated.CompletedAt.Should().NotBeNull();
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}
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[Fact]
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public async Task DeadlinePassed_MonitorMarksNonCompliant()
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{
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using var scope = _fixture.Services.CreateScope();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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await CreateSofaSepsisBundleAsync(scope);
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var bundle = await db.SepsisBundles.SingleAsync();
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bundle.DeadlineAt = DateTimeOffset.UtcNow.AddHours(-1);
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await db.SaveChangesAsync();
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var monitor = new SepsisBundleMonitorService(
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_fixture.Services,
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_fixture.Services.GetRequiredService<ClinicalMetrics>(),
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_fixture.Services.GetRequiredService<ILogger<SepsisBundleMonitorService>>());
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await monitor.ScanOverdueBundlesAsync(CancellationToken.None);
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var updated = await db.SepsisBundles.AsNoTracking().SingleAsync();
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updated.ComplianceStatus.Should().Be(SepsisBundleComplianceStatus.NonCompliant);
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updated.CompletedAt.Should().BeNull(
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"the monitor marks overdue bundles non-compliant without setting CompletedAt — " +
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"elements are still incomplete");
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var elements = await db.SepsisBundleElements
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.AsNoTracking()
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.Where(e => e.BundleId == updated.Id)
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.ToListAsync();
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elements.Should().AllSatisfy(e =>
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e.Status.Should().Be(SepsisBundleElementStatus.Pending,
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"the monitor does not complete individual elements"));
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}
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}
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