{
  "ConnectionStrings": {
    "DefaultConnection": "Host=localhost;Port=5436;Database=vigilcare;Username=postgres;Password=password"
  },
  "Redis": {
    "ConnectionString": "localhost:6382"
  },
  "Seq": {
    "ServerUrl": "http://localhost:5345"
  },
  "Serilog": {
    "Using": [ "Serilog.Sinks.Console", "Serilog.Sinks.Seq" ],
    "MinimumLevel": {
      "Default": "Information",
      "Override": {
        "Microsoft.AspNetCore": "Warning",
        "Microsoft.EntityFrameworkCore.Database.Command": "Information"
      }
    },
    "WriteTo": [
      { "Name": "Console" },
      {
        "Name": "Seq",
        "Args": {
          "serverUrl": "http://localhost:5345"
        }
      }
    ],
    "Enrich": [ "FromLogContext", "WithMachineName", "WithThreadId" ]
  },
  "Logging": {
    "LogLevel": {
      "Default": "Information",
      "Microsoft.AspNetCore": "Warning",
      "Microsoft.EntityFrameworkCore.Database.Command": "Information"
    }
  },
  "AllowedHosts": "*",
  "Dashboard": {
    "CorsOrigins": [ "http://localhost:5173" ]
  },
  "Kafka": {
    "BootstrapServers": "localhost:9092",
    "Topics": {
      "ObservationRecorded": "observation.recorded",
      "AlertGenerated": "alert.generated",
      "EncounterStatusChanged": "encounter.status.changed"
    },
    "NumPartitions": 6,
    "OutboxBatchSize": 100,
    "OutboxPollIntervalMs": 1000
  },
  "Elasticsearch": {
    "Uri": "http://localhost:9200",
    "Indices": {
      "PatientEncounters": "patient_encounters",
      "Observations": "observations",
      "ClinicalAlerts": "clinical_alerts"
    }
  },
  "RabbitMq": {
    "Host": "localhost",
    "Port": 5674,
    "Username": "guest",
    "Password": "guest",
    "PagingAckTimeoutMs": 300000
  },
  "Minio": {
    "Endpoint": "localhost:9005",
    "AccessKey": "minioadmin",
    "SecretKey": "minioadmin",
    "BucketName": "vigilcare",
    "UseSSL": false
  },
  "ReconciliationJobs": {
    "IntervalMinutes": 30,
    "UnacknowledgedAlertThresholdMinutes": 30,
    "PendingOrderThresholdHours": 4,
    "NoObservationThresholdHours": 2
  },
  "DataLake": {
    "FlushCount": 1000,
    "FlushIntervalSeconds": 300
  },
  "TrendDetection": {
    "WindowMinutes": 30,
    "MaxHistoryEntries": 10,
    "HistoryTtlSeconds": 7200,
    "RateThresholdsPerMinute": {
      "HEART_RATE": 0.5,
      "RESP_RATE": 0.3,
      "SYSTOLIC_BP": 1.0,
      "TEMP_C": 0.05,
      "SPO2": 0.2
    }
  },
  "AlertSuppression": {
    "DefaultWindowMinutes": 30
  },
  "MedicationCorrelation": {
    "CorrelationWindowMinutes": 90,
    "DrugVitalMappings": {
      "metoprolol": ["SYSTOLIC_BP", "HEART_RATE", "DIASTOLIC_BP"],
      "labetalol": ["SYSTOLIC_BP", "HEART_RATE", "DIASTOLIC_BP"],
      "atenolol": ["SYSTOLIC_BP", "HEART_RATE", "DIASTOLIC_BP"],
      "propranolol": ["SYSTOLIC_BP", "HEART_RATE", "DIASTOLIC_BP"],
      "esmolol": ["SYSTOLIC_BP", "HEART_RATE", "DIASTOLIC_BP"],
      "carvedilol": ["SYSTOLIC_BP", "HEART_RATE", "DIASTOLIC_BP"],

      "norepinephrine": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE"],
      "epinephrine": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE", "GLUCOSE_MG_DL"],
      "vasopressin": ["SYSTOLIC_BP", "DIASTOLIC_BP"],
      "dopamine": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE"],
      "dobutamine": ["SYSTOLIC_BP", "HEART_RATE"],
      "phenylephrine": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE"],

      "diltiazem": ["HEART_RATE", "SYSTOLIC_BP", "DIASTOLIC_BP"],
      "verapamil": ["HEART_RATE", "SYSTOLIC_BP", "DIASTOLIC_BP"],
      "amlodipine": ["SYSTOLIC_BP", "DIASTOLIC_BP"],
      "nicardipine": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE"],

      "nitroglycerin": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE"],
      "nitroprusside": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE"],
      "hydralazine": ["SYSTOLIC_BP", "DIASTOLIC_BP", "HEART_RATE"],

      "morphine": ["RESP_RATE", "SPO2", "SYSTOLIC_BP", "HEART_RATE"],
      "fentanyl": ["RESP_RATE", "SPO2", "HEART_RATE"],
      "hydromorphone": ["RESP_RATE", "SPO2", "SYSTOLIC_BP"],
      "remifentanil": ["RESP_RATE", "SPO2", "HEART_RATE"],

      "propofol": ["RESP_RATE", "SPO2", "SYSTOLIC_BP", "HEART_RATE"],
      "midazolam": ["RESP_RATE", "SPO2"],
      "lorazepam": ["RESP_RATE", "SPO2"],
      "ketamine": ["HEART_RATE", "SYSTOLIC_BP", "RESP_RATE"],

      "amiodarone": ["HEART_RATE", "SYSTOLIC_BP"],
      "adenosine": ["HEART_RATE"],
      "digoxin": ["HEART_RATE"],
      "atropine": ["HEART_RATE"],

      "heparin": ["HEART_RATE"],

      "acetaminophen": ["TEMP_C"],
      "ibuprofen": ["TEMP_C"],

      "insulin": ["GLUCOSE_MG_DL"],
      "dextrose": ["GLUCOSE_MG_DL"],
      "glucagon": ["GLUCOSE_MG_DL"],

      "dexamethasone": ["GLUCOSE_MG_DL", "TEMP_C"],
      "methylprednisolone": ["GLUCOSE_MG_DL", "TEMP_C"],
      "hydrocortisone": ["GLUCOSE_MG_DL", "TEMP_C"],
      "prednisone": ["GLUCOSE_MG_DL", "TEMP_C"],

      "furosemide": ["SYSTOLIC_BP", "DIASTOLIC_BP"],

      "albuterol": ["HEART_RATE", "SPO2"]
    }
  }
}