feature: Sepsis Early Warning Engine
This commit is contained in:
@@ -0,0 +1,161 @@
|
||||
using System.Text.Json;
|
||||
using Microsoft.EntityFrameworkCore;
|
||||
using StackExchange.Redis;
|
||||
|
||||
public class SirsDetector
|
||||
{
|
||||
// 30 minutes in seconds. This is a clinical parameter: SIRS criteria evaluated
|
||||
// outside a 30-minute window are clinically stale. The TTL enforces the window
|
||||
// automatically — no cleanup job required.
|
||||
private const int SirsTtlSeconds = 1800;
|
||||
|
||||
private readonly IConnectionMultiplexer _redis;
|
||||
private readonly IServiceProvider _services;
|
||||
private readonly ILogger<SirsDetector> _logger;
|
||||
|
||||
public SirsDetector(
|
||||
IConnectionMultiplexer redis,
|
||||
IServiceProvider services,
|
||||
ILogger<SirsDetector> logger)
|
||||
{
|
||||
_redis = redis;
|
||||
_services = services;
|
||||
_logger = logger;
|
||||
}
|
||||
|
||||
public async Task<SirsResult> ProcessObservationAsync(
|
||||
Guid encounterId,
|
||||
Guid patientId,
|
||||
string observationCode,
|
||||
decimal value,
|
||||
CancellationToken ct = default)
|
||||
{
|
||||
// Fast exit for non-SIRS codes. The sepsis engine subscribes to the full
|
||||
// observation.recorded stream — the majority of messages (SpO2, potassium, glucose)
|
||||
// are not SIRS-relevant and are discarded here without touching Redis or PostgreSQL.
|
||||
if (!SirsEvaluator.SirsCodes.Contains(observationCode))
|
||||
return SirsResult.NotSirsCode;
|
||||
|
||||
var cache = _redis.GetDatabase();
|
||||
var key = SirsEvaluator.CriterionKey(encounterId, observationCode);
|
||||
|
||||
if (SirsEvaluator.MeetsCriterion(observationCode, value))
|
||||
{
|
||||
// SET with EX refreshes the TTL on every qualifying observation.
|
||||
// A patient with tachycardia posting a reading every 60 seconds will keep
|
||||
// sirs:{id}:HEART_RATE alive for 30 minutes after the LAST qualifying reading,
|
||||
// not the first — the window slides forward with each new abnormal value.
|
||||
await cache.StringSetAsync(key, "1", TimeSpan.FromSeconds(SirsTtlSeconds));
|
||||
|
||||
_logger.LogDebug("SIRS criterion set: {Key} (TTL={Ttl}s)", key, SirsTtlSeconds);
|
||||
}
|
||||
else
|
||||
{
|
||||
// Criterion no longer met — remove the key immediately rather than waiting
|
||||
// for TTL expiry. If a patient's temperature normalises at 37.0 °C, the
|
||||
// fever criterion must stop contributing to the count right away.
|
||||
// Without this DEL, a recovered criterion could persist for up to 30 minutes
|
||||
// and falsely sustain a SEPSIS_WARNING count.
|
||||
await cache.KeyDeleteAsync(key);
|
||||
|
||||
_logger.LogDebug("SIRS criterion cleared: {Key}", key);
|
||||
}
|
||||
|
||||
// Count active criteria in one MGET round-trip.
|
||||
// MGET is O(N) where N = number of keys requested (4 here, always).
|
||||
// Never use KEYS pattern for this check: KEYS scans the entire keyspace
|
||||
// and blocks all other Redis operations until the scan completes.
|
||||
var allKeys = SirsEvaluator.AllCriterionKeys(encounterId);
|
||||
var values = await cache.StringGetAsync(allKeys);
|
||||
var activeCount = values.Count(v => v.HasValue);
|
||||
|
||||
_logger.LogDebug(
|
||||
"SIRS state for encounter {Id}: {Active}/4 criteria active after {Code}={Value}",
|
||||
encounterId, activeCount, observationCode, value);
|
||||
|
||||
if (activeCount < 2)
|
||||
return SirsResult.InsufficientCriteria(activeCount);
|
||||
|
||||
// Two or more criteria are active — attempt to create the alert.
|
||||
var created = await TryCreateAlertAsync(encounterId, patientId, activeCount, ct);
|
||||
return created ? SirsResult.AlertCreated : SirsResult.AlertAlreadyOpen;
|
||||
}
|
||||
|
||||
// Creates the SEPSIS_WARNING alert and its outbox event in one atomic transaction.
|
||||
// The INSERT WHERE NOT EXISTS pattern makes this safe under at-least-once delivery:
|
||||
// if the consumer crashes after the INSERT but before committing the Kafka offset,
|
||||
// the observation is reprocessed on restart. The second run hits the WHERE NOT EXISTS
|
||||
// subquery, finds the existing open alert, inserts 0 rows, and returns false — no
|
||||
// duplicate alert, no duplicate outbox event.
|
||||
private async Task<bool> TryCreateAlertAsync(
|
||||
Guid encounterId,
|
||||
Guid patientId,
|
||||
int activeCount,
|
||||
CancellationToken ct)
|
||||
{
|
||||
using var scope = _services.CreateScope();
|
||||
var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
|
||||
|
||||
await using var tx = await db.Database.BeginTransactionAsync(ct);
|
||||
|
||||
var alertId = Guid.NewGuid();
|
||||
var triggeredAt = DateTimeOffset.UtcNow;
|
||||
var details =
|
||||
$"SIRS criteria met: {activeCount} of 4 criteria active within the 30-minute window.";
|
||||
|
||||
// One SQL round-trip: check + insert atomically.
|
||||
// status IN ('OPEN', 'ESCALATED') prevents re-creating an alert that has been
|
||||
// escalated but not yet resolved — the patient is still in danger.
|
||||
var affected = await db.Database.ExecuteSqlInterpolatedAsync($"""
|
||||
INSERT INTO clinical_alerts
|
||||
(id, encounter_id, patient_id, alert_type, severity, details, status, triggered_at)
|
||||
SELECT {alertId}, {encounterId}, {patientId},
|
||||
'SEPSIS_WARNING', 'CRITICAL', {details}, 'OPEN', {triggeredAt}
|
||||
WHERE NOT EXISTS (
|
||||
SELECT 1 FROM clinical_alerts
|
||||
WHERE encounter_id = {encounterId}
|
||||
AND alert_type = 'SEPSIS_WARNING'
|
||||
AND status IN ('OPEN', 'ESCALATED')
|
||||
)
|
||||
""", ct);
|
||||
|
||||
if (affected == 0)
|
||||
{
|
||||
await tx.RollbackAsync(ct);
|
||||
_logger.LogDebug(
|
||||
"SEPSIS_WARNING already open for encounter {Id} — no new alert", encounterId);
|
||||
return false;
|
||||
}
|
||||
|
||||
// Alert was created — write the outbox event in the same transaction.
|
||||
// The relay (Phase 3) will publish to alert.generated, which Phase 6's
|
||||
// notification worker reads to page the attending physician via RabbitMQ.
|
||||
db.OutboxEvents.Add(new OutboxEvent
|
||||
{
|
||||
Id = Guid.NewGuid(),
|
||||
Topic = "alert.generated",
|
||||
Payload = JsonSerializer.Serialize(new
|
||||
{
|
||||
alertId,
|
||||
encounterId,
|
||||
patientId,
|
||||
alertType = AlertType.SepsisWarning.ToDbString(),
|
||||
severity = "Critical",
|
||||
triggeredAt,
|
||||
partitionKey = encounterId.ToString()
|
||||
}),
|
||||
PartitionKey = encounterId.ToString(),
|
||||
CreatedAt = DateTimeOffset.UtcNow
|
||||
});
|
||||
|
||||
await db.SaveChangesAsync(ct);
|
||||
await tx.CommitAsync(ct);
|
||||
|
||||
_logger.LogWarning(
|
||||
"SEPSIS_WARNING alert {AlertId} created for encounter {EncounterId} " +
|
||||
"— {Active}/4 SIRS criteria active",
|
||||
alertId, encounterId, activeCount);
|
||||
|
||||
return true;
|
||||
}
|
||||
}
|
||||
Reference in New Issue
Block a user