feature: Sepsis Engine Refactor: Remove SIRS, Rewire qSOFA + Bundle
Frontend: GCS Entry, SOFA Display, Sepsis UI Refactor
This commit is contained in:
@@ -34,13 +34,10 @@ public class SepsisEngineService : BackgroundService
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};
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using var consumer = new ConsumerBuilder<string, string>(config).Build();
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// Subscribes to observation.recorded only.
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// The es-indexer consumes all three topics; the sepsis engine only needs one.
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// Subscribing to a superset of needed topics would waste CPU deserializing
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// alert and encounter events that this engine discards immediately.
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consumer.Subscribe(_kafkaOptions.Topics.ObservationRecorded);
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_logger.LogInformation("SepsisEngineService started — consumer group: sepsis-engine");
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_logger.LogInformation(
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"SepsisEngineService started — consumer group: sepsis-engine (qSOFA screening only)");
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try
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{
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@@ -54,19 +51,9 @@ public class SepsisEngineService : BackgroundService
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var evt = JsonSerializer.Deserialize<SepsisObservationEvent>(
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result.Message.Value, EventJsonOptions)!;
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// Create a scope per message — both detectors are scoped and
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// each owns a fresh DbContext when creating alerts.
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using var scope = _services.CreateScope();
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var sirsDetector = scope.ServiceProvider.GetRequiredService<SirsDetector>();
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var qsofaDetector = scope.ServiceProvider.GetRequiredService<QsofaDetector>();
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var sirsOutcome = await sirsDetector.ProcessObservationAsync(
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evt.EncounterId,
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evt.PatientId,
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evt.ObservationCode,
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evt.Value,
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stoppingToken);
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var qsofaOutcome = await qsofaDetector.ProcessObservationAsync(
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evt.EncounterId,
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evt.PatientId,
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@@ -74,19 +61,12 @@ public class SepsisEngineService : BackgroundService
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evt.Value,
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stoppingToken);
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if (sirsOutcome.Outcome == SirsOutcome.AlertCreated)
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_logger.LogWarning(
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"SEPSIS_WARNING created via SepsisEngine " +
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"— encounter={EncounterId} code={Code} value={Value}",
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evt.EncounterId, evt.ObservationCode, evt.Value);
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if (qsofaOutcome.Outcome == QsofaOutcome.AlertCreated)
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_logger.LogWarning(
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"QSOFA_WARNING created via SepsisEngine " +
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_logger.LogInformation(
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"QSOFA_SCREEN created via SepsisEngine " +
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"— encounter={EncounterId} code={Code} value={Value}",
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evt.EncounterId, evt.ObservationCode, evt.Value);
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// Commit only after successful processing.
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consumer.Commit(result);
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}
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catch (OperationCanceledException)
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@@ -98,8 +78,6 @@ public class SepsisEngineService : BackgroundService
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_logger.LogError(ex,
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"SepsisEngine failed on topic={Topic} offset={Offset} — not committing",
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result?.Topic, result?.Offset.Value);
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// Back off before retrying so a persistent failure (e.g., Redis down)
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// does not spin the loop at maximum throughput.
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await Task.Delay(2000, stoppingToken);
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}
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}
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@@ -18,13 +18,18 @@ public class ClinicalAlertConfiguration : IEntityTypeConfiguration<ClinicalAlert
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"'CRITICAL_SPO2', 'CRITICAL_RESP_RATE', 'CRITICAL_WBC_K_UL', " +
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"'CRITICAL_SYSTOLIC_BP', 'CRITICAL_DIASTOLIC_BP', 'CRITICAL_LACTATE_MMOL_L', " +
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"'CRITICAL_AVPU', 'CRITICAL_GLUCOSE_MG_DL', " +
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"'CRITICAL_PAO2_MMHG', 'CRITICAL_PLATELET_K_UL', " +
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"'CRITICAL_BILIRUBIN_MG_DL', 'CRITICAL_CREATININE_MG_DL', " +
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"'WARNING_HEART_RATE', 'WARNING_TEMP_C', 'WARNING_POTASSIUM_MEQ_L', " +
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"'WARNING_SPO2', 'WARNING_RESP_RATE', 'WARNING_WBC_K_UL', " +
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"'WARNING_SYSTOLIC_BP', 'WARNING_DIASTOLIC_BP', 'WARNING_LACTATE_MMOL_L', " +
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"'WARNING_GLUCOSE_MG_DL', " +
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"'WARNING_PAO2_MMHG', 'WARNING_PLATELET_K_UL', " +
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"'WARNING_BILIRUBIN_MG_DL', 'WARNING_CREATININE_MG_DL', " +
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"'NEWS2_WARNING', 'NEWS2_EMERGENCY', " +
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"'RAPID_DETERIORATION', 'QSOFA_WARNING', " +
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"'GCS_CRITICAL', 'GCS_WARNING')");
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"'RAPID_DETERIORATION', 'QSOFA_WARNING', 'QSOFA_SCREEN', " +
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"'GCS_CRITICAL', 'GCS_WARNING', " +
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"'SOFA_SEPSIS', 'SOFA_WARNING')");
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});
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builder.HasKey(a => a.Id);
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builder.Property(a => a.Id).HasColumnName("id").HasDefaultValueSql("gen_random_uuid()");
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@@ -1,5 +1,6 @@
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public enum AlertType
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{
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[Obsolete("Legacy — replaced by SOFA_SEPSIS in Phase 27. Retained for historical alert queries.")]
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SepsisWarning,
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CriticalHeartRate,
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CriticalTempC,
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@@ -30,8 +31,11 @@ public enum AlertType
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RapidDeterioration,
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[Obsolete("Legacy — replaced by QSOFA_SCREEN in Phase 27. Retained for historical alert queries.")]
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QsofaWarning,
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QsofaScreen,
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GcsCritical,
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GcsWarning,
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@@ -90,6 +94,7 @@ public static class AlertTypeExtensions
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AlertType.WarningCreatinineMgDl => "WARNING_CREATININE_MG_DL",
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AlertType.SofaSepsis => "SOFA_SEPSIS",
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AlertType.SofaWarning => "SOFA_WARNING",
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AlertType.QsofaScreen => "QSOFA_SCREEN",
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_ => throw new ArgumentOutOfRangeException(nameof(t))
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};
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@@ -121,6 +126,7 @@ public static class AlertTypeExtensions
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"NEWS2_EMERGENCY" => AlertType.News2Emergency,
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"RAPID_DETERIORATION" => AlertType.RapidDeterioration,
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"QSOFA_WARNING" => AlertType.QsofaWarning,
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"QSOFA_SCREEN" => AlertType.QsofaScreen,
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"GCS_CRITICAL" => AlertType.GcsCritical,
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"GCS_WARNING" => AlertType.GcsWarning,
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"CRITICAL_PAO2_MMHG" => AlertType.CriticalPao2MmHg,
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@@ -189,7 +195,7 @@ public static class AlertTypeExtensions
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AlertType.RapidDeterioration => false,
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AlertType.GcsCritical => false, // trajectory alerts are never suppressed
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AlertType.SofaSepsis => false,
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_ => true // all Warning* types, News2Warning, and QsofaWarning
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_ => true // all Warning* types, News2Warning, QsofaScreen, SofaWarning, GcsWarning
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};
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public static string? ObservationCodeForWarning(this AlertType t) => t switch
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@@ -141,6 +141,8 @@ public class GcsDetector
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}
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}
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AlertCreationGuard.EnsureAllowed(alertType);
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using var scope = _services.CreateScope();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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+1085
File diff suppressed because it is too large
Load Diff
@@ -0,0 +1,44 @@
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using Microsoft.EntityFrameworkCore.Migrations;
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#nullable disable
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namespace VigilCareClinicalAPI.Migrations
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{
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/// <inheritdoc />
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public partial class AddQsofaScreenAlertTypecs : Migration
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{
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/// <inheritdoc />
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protected override void Up(MigrationBuilder migrationBuilder)
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{
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migrationBuilder.Sql("""
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ALTER TABLE clinical_alerts DROP CONSTRAINT chk_clinical_alerts_alert_type;
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ALTER TABLE clinical_alerts ADD CONSTRAINT chk_clinical_alerts_alert_type
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CHECK (alert_type IN (
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'SEPSIS_WARNING',
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'CRITICAL_HEART_RATE', 'CRITICAL_TEMP_C', 'CRITICAL_POTASSIUM_MEQ_L',
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'CRITICAL_SPO2', 'CRITICAL_RESP_RATE', 'CRITICAL_WBC_K_UL',
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'CRITICAL_SYSTOLIC_BP', 'CRITICAL_DIASTOLIC_BP', 'CRITICAL_LACTATE_MMOL_L',
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'CRITICAL_AVPU', 'CRITICAL_GLUCOSE_MG_DL',
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'CRITICAL_PAO2_MMHG', 'CRITICAL_PLATELET_K_UL',
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'CRITICAL_BILIRUBIN_MG_DL', 'CRITICAL_CREATININE_MG_DL',
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'WARNING_HEART_RATE', 'WARNING_TEMP_C', 'WARNING_POTASSIUM_MEQ_L',
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'WARNING_SPO2', 'WARNING_RESP_RATE', 'WARNING_WBC_K_UL',
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'WARNING_SYSTOLIC_BP', 'WARNING_DIASTOLIC_BP', 'WARNING_LACTATE_MMOL_L',
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'WARNING_GLUCOSE_MG_DL',
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'WARNING_PAO2_MMHG', 'WARNING_PLATELET_K_UL',
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'WARNING_BILIRUBIN_MG_DL', 'WARNING_CREATININE_MG_DL',
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'NEWS2_WARNING', 'NEWS2_EMERGENCY',
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'RAPID_DETERIORATION', 'QSOFA_WARNING', 'QSOFA_SCREEN',
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'GCS_CRITICAL', 'GCS_WARNING',
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'SOFA_SEPSIS', 'SOFA_WARNING'
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));
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""");
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}
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/// <inheritdoc />
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protected override void Down(MigrationBuilder migrationBuilder)
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{
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}
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}
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}
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@@ -156,7 +156,7 @@ namespace VigilCareClinicalAPI.Migrations
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b.ToTable("clinical_alerts", null, t =>
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{
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t.HasCheckConstraint("chk_clinical_alerts_alert_type", "alert_type IN ('SEPSIS_WARNING', 'CRITICAL_HEART_RATE', 'CRITICAL_TEMP_C', 'CRITICAL_POTASSIUM_MEQ_L', 'CRITICAL_SPO2', 'CRITICAL_RESP_RATE', 'CRITICAL_WBC_K_UL', 'CRITICAL_SYSTOLIC_BP', 'CRITICAL_DIASTOLIC_BP', 'CRITICAL_LACTATE_MMOL_L', 'CRITICAL_AVPU', 'CRITICAL_GLUCOSE_MG_DL', 'WARNING_HEART_RATE', 'WARNING_TEMP_C', 'WARNING_POTASSIUM_MEQ_L', 'WARNING_SPO2', 'WARNING_RESP_RATE', 'WARNING_WBC_K_UL', 'WARNING_SYSTOLIC_BP', 'WARNING_DIASTOLIC_BP', 'WARNING_LACTATE_MMOL_L', 'WARNING_GLUCOSE_MG_DL', 'NEWS2_WARNING', 'NEWS2_EMERGENCY', 'RAPID_DETERIORATION', 'QSOFA_WARNING', 'GCS_CRITICAL', 'GCS_WARNING')");
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t.HasCheckConstraint("chk_clinical_alerts_alert_type", "alert_type IN ('SEPSIS_WARNING', 'CRITICAL_HEART_RATE', 'CRITICAL_TEMP_C', 'CRITICAL_POTASSIUM_MEQ_L', 'CRITICAL_SPO2', 'CRITICAL_RESP_RATE', 'CRITICAL_WBC_K_UL', 'CRITICAL_SYSTOLIC_BP', 'CRITICAL_DIASTOLIC_BP', 'CRITICAL_LACTATE_MMOL_L', 'CRITICAL_AVPU', 'CRITICAL_GLUCOSE_MG_DL', 'CRITICAL_PAO2_MMHG', 'CRITICAL_PLATELET_K_UL', 'CRITICAL_BILIRUBIN_MG_DL', 'CRITICAL_CREATININE_MG_DL', 'WARNING_HEART_RATE', 'WARNING_TEMP_C', 'WARNING_POTASSIUM_MEQ_L', 'WARNING_SPO2', 'WARNING_RESP_RATE', 'WARNING_WBC_K_UL', 'WARNING_SYSTOLIC_BP', 'WARNING_DIASTOLIC_BP', 'WARNING_LACTATE_MMOL_L', 'WARNING_GLUCOSE_MG_DL', 'WARNING_PAO2_MMHG', 'WARNING_PLATELET_K_UL', 'WARNING_BILIRUBIN_MG_DL', 'WARNING_CREATININE_MG_DL', 'NEWS2_WARNING', 'NEWS2_EMERGENCY', 'RAPID_DETERIORATION', 'QSOFA_WARNING', 'QSOFA_SCREEN', 'GCS_CRITICAL', 'GCS_WARNING', 'SOFA_SEPSIS', 'SOFA_WARNING')");
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t.HasCheckConstraint("chk_clinical_alerts_severity", "severity IN ('WARNING', 'CRITICAL')");
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@@ -1,7 +0,0 @@
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public enum SirsOutcome
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{
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NotSirsCode,
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InsufficientCriteria,
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AlertCreated,
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AlertAlreadyOpen
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}
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@@ -1,11 +0,0 @@
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// Discriminated result — allows tests and callers to assert the exact outcome
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// without inspecting PostgreSQL or Redis directly.
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public record SirsResult(SirsOutcome Outcome, int ActiveCount = 0)
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{
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public static readonly SirsResult NotSirsCode = new(SirsOutcome.NotSirsCode);
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public static readonly SirsResult AlertCreated = new(SirsOutcome.AlertCreated);
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public static readonly SirsResult AlertAlreadyOpen = new(SirsOutcome.AlertAlreadyOpen);
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public static SirsResult InsufficientCriteria(int count) =>
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new(SirsOutcome.InsufficientCriteria, count);
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}
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@@ -199,6 +199,8 @@ public class News2Detector
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}
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}
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AlertCreationGuard.EnsureAllowed(alertType);
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using var scope = _services.CreateScope();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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@@ -11,19 +11,12 @@ public sealed class ClinicalMetrics
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"Total observations ingested, labeled by observation code and source.",
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labelNames: new[] { "observation_code", "source" });
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// Labeled by alert_type (THRESHOLD_BREACH, SEPSIS_WARNING, QSOFA_WARNING) and severity
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// (Critical, Warning) so the dashboard can show Critical vs Warning rates separately.
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// Labeled by alert_type and severity (e.g. QSOFA_SCREEN/WARNING, SOFA_SEPSIS/CRITICAL).
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public readonly Counter ClinicalAlertsTotal = Metrics.CreateCounter(
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"clinical_alerts_total",
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"Total clinical alerts generated, labeled by type and severity.",
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labelNames: new[] { "alert_type", "severity" });
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// Incremented only when INSERT WHERE NOT EXISTS succeeds — duplicate-suppressed
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// SIRS detections do not count. This is the true detection rate, not the evaluation rate.
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public readonly Counter SirsDetectionsTotal = Metrics.CreateCounter(
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"sirs_detections_total",
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"Total SEPSIS_WARNING alerts generated by the sepsis detection engine.");
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public readonly Counter News2ScoresTotal = Metrics.CreateCounter(
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"news2_scores_total",
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"Total NEWS2 scores computed, labeled by risk level.",
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@@ -48,7 +41,7 @@ public sealed class ClinicalMetrics
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public readonly Counter QsofaDetectionsTotal = Metrics.CreateCounter(
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"qsofa_detections_total",
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"Total QSOFA_WARNING alerts generated by the qSOFA scoring engine.");
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"Total QSOFA_SCREEN alerts generated by the qSOFA screening engine.");
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public readonly Counter SepsisBundleComplianceTotal = Metrics.CreateCounter(
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"sepsis_bundle_compliance_total",
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@@ -105,7 +105,6 @@ try
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builder.Services.AddScoped<IQsofaService, QsofaService>();
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builder.Services.AddScoped<ISepsisBundleService, SepsisBundleService>();
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builder.Services.AddScoped<SepsisAlertHandler>();
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builder.Services.AddScoped<SirsDetector>();
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builder.Services.AddScoped<QsofaDetector>();
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builder.Services.AddScoped<UnacknowledgedAlertsCheck>();
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builder.Services.AddScoped<PendingOrdersCheck>();
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@@ -0,0 +1,9 @@
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public static class AlertCreationGuard
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{
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public static void EnsureAllowed(AlertType alertType)
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{
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if (alertType == AlertType.SepsisWarning)
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throw new InvalidOperationException(
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"SEPSIS_WARNING is deprecated. Use SOFA_SEPSIS for sepsis detection.");
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}
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}
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@@ -1,5 +1,9 @@
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using StackExchange.Redis;
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// qSOFA criteria (Sepsis-3 bedside screen):
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// - Respiratory rate ≥ 22 breaths/min
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// - Systolic blood pressure ≤ 100 mmHg
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// - Altered mentation: AVPU ≥ 1 or GCS total < 15 (via SyncAlteredMentationAsync)
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public static class QsofaCalculator
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{
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public static readonly IReadOnlyList<string> QsofaCodes = new[]
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@@ -5,7 +5,6 @@ using StackExchange.Redis;
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public class QsofaDetector
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{
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// 30 minutes in seconds — same sliding window as SIRS.
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private const int QsofaTtlSeconds = 1800;
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private readonly IConnectionMultiplexer _redis;
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@@ -42,30 +41,13 @@ public class QsofaDetector
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{
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await cache.StringSetAsync(
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key, value.ToString(), TimeSpan.FromSeconds(QsofaTtlSeconds));
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_logger.LogDebug("qSOFA criterion set: {Key}={Value} (TTL={Ttl}s)",
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key, value, QsofaTtlSeconds);
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}
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else
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{
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await cache.KeyDeleteAsync(key);
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_logger.LogDebug("qSOFA criterion cleared: {Key}", key);
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}
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var allKeys = QsofaCalculator.AllCriterionKeys(encounterId);
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var values = await cache.StringGetAsync(allKeys);
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var activeCount = QsofaCalculator.CountActiveCriteria(values);
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_logger.LogDebug(
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"qSOFA state for encounter {Id}: {Active}/3 criteria active after {Code}={Value}",
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encounterId, activeCount, observationCode, value);
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if (activeCount < 2)
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return QsofaResult.InsufficientCriteria(activeCount);
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var created = await TryCreateAlertAsync(encounterId, patientId, activeCount, values, ct);
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return created ? QsofaResult.AlertCreated : QsofaResult.AlertAlreadyOpen;
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return await EvaluateAndMaybeAlertAsync(encounterId, patientId, ct);
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}
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public async Task<QsofaResult> SyncAlteredMentationAsync(
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@@ -85,16 +67,18 @@ public class QsofaDetector
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var total = GcsCalculator.ComputeTotal(eye, verbal, motor)!.Value;
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if (QsofaCalculator.MeetsGcsAlteredMentation(total))
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{
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await cache.StringSetAsync(
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avpuKey, "1", TimeSpan.FromSeconds(QsofaTtlSeconds));
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}
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await cache.StringSetAsync(avpuKey, "1", TimeSpan.FromSeconds(QsofaTtlSeconds));
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else
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{
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await cache.KeyDeleteAsync(avpuKey);
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}
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}
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return await EvaluateAndMaybeAlertAsync(encounterId, patientId, ct);
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}
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private async Task<QsofaResult> EvaluateAndMaybeAlertAsync(
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Guid encounterId, Guid patientId, CancellationToken ct)
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{
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var cache = _redis.GetDatabase();
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var allKeys = QsofaCalculator.AllCriterionKeys(encounterId);
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var values = await cache.StringGetAsync(allKeys);
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var activeCount = QsofaCalculator.CountActiveCriteria(values);
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@@ -102,17 +86,19 @@ public class QsofaDetector
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if (activeCount < 2)
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return QsofaResult.InsufficientCriteria(activeCount);
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var created = await TryCreateAlertAsync(encounterId, patientId, activeCount, values, ct);
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var created = await TryCreateScreenAlertAsync(encounterId, patientId, activeCount, values, ct);
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return created ? QsofaResult.AlertCreated : QsofaResult.AlertAlreadyOpen;
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}
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private async Task<bool> TryCreateAlertAsync(
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private async Task<bool> TryCreateScreenAlertAsync(
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Guid encounterId,
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Guid patientId,
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int activeCount,
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RedisValue[] criterionValues,
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CancellationToken ct)
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{
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AlertCreationGuard.EnsureAllowed(AlertType.QsofaScreen);
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using var scope = _services.CreateScope();
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var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
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@@ -120,17 +106,21 @@ public class QsofaDetector
|
||||
|
||||
var alertId = Guid.NewGuid();
|
||||
var triggeredAt = DateTimeOffset.UtcNow;
|
||||
var details = BuildDetails(activeCount, criterionValues);
|
||||
var activeCriteria = BuildActiveCriteriaList(criterionValues);
|
||||
var details =
|
||||
$"qSOFA score ≥ 2 (criteria: {activeCriteria}). " +
|
||||
"Recommend: order SOFA labs (PaO2/FiO2, platelets, bilirubin, creatinine) " +
|
||||
"to evaluate for organ dysfunction.";
|
||||
|
||||
var affected = await db.Database.ExecuteSqlInterpolatedAsync($"""
|
||||
INSERT INTO clinical_alerts
|
||||
(id, encounter_id, patient_id, alert_type, severity, details, status, triggered_at)
|
||||
SELECT {alertId}, {encounterId}, {patientId},
|
||||
'QSOFA_WARNING', 'CRITICAL', {details}, 'OPEN', {triggeredAt}
|
||||
'QSOFA_SCREEN', 'WARNING', {details}, 'OPEN', {triggeredAt}
|
||||
WHERE NOT EXISTS (
|
||||
SELECT 1 FROM clinical_alerts
|
||||
WHERE encounter_id = {encounterId}
|
||||
AND alert_type = 'QSOFA_WARNING'
|
||||
AND alert_type = 'QSOFA_SCREEN'
|
||||
AND status IN ('OPEN', 'ESCALATED')
|
||||
)
|
||||
""", ct);
|
||||
@@ -138,8 +128,6 @@ public class QsofaDetector
|
||||
if (affected == 0)
|
||||
{
|
||||
await tx.RollbackAsync(ct);
|
||||
_logger.LogDebug(
|
||||
"QSOFA_WARNING already open for encounter {Id} — no new alert", encounterId);
|
||||
return false;
|
||||
}
|
||||
|
||||
@@ -152,8 +140,8 @@ public class QsofaDetector
|
||||
alertId,
|
||||
encounterId,
|
||||
patientId,
|
||||
alertType = AlertType.QsofaWarning.ToDbString(),
|
||||
severity = "Critical",
|
||||
alertType = AlertType.QsofaScreen.ToDbString(),
|
||||
severity = AlertSeverity.Warning.ToDbString(),
|
||||
details,
|
||||
triggeredAt,
|
||||
partitionKey = encounterId.ToString()
|
||||
@@ -167,24 +155,22 @@ public class QsofaDetector
|
||||
|
||||
_metrics.QsofaDetectionsTotal.Inc();
|
||||
_metrics.ClinicalAlertsTotal
|
||||
.WithLabels(AlertType.QsofaWarning.ToDbString(), AlertSeverity.Critical.ToDbString())
|
||||
.WithLabels(AlertType.QsofaScreen.ToDbString(), AlertSeverity.Warning.ToDbString())
|
||||
.Inc();
|
||||
|
||||
using (LogContext.PushProperty("EncounterId", encounterId))
|
||||
using (LogContext.PushProperty("PatientId", patientId))
|
||||
{
|
||||
_logger.LogWarning(
|
||||
"QSOFA_WARNING created. ActiveCriteriaCount={Count} AlertId={AlertId}",
|
||||
"QSOFA_SCREEN created. ActiveCriteriaCount={Count} AlertId={AlertId}",
|
||||
activeCount, alertId);
|
||||
}
|
||||
|
||||
var handler = scope.ServiceProvider.GetRequiredService<SepsisAlertHandler>();
|
||||
await handler.OnSepsisAlertCreatedAsync(encounterId, alertId, AlertType.QsofaWarning, ct);
|
||||
|
||||
// Screening alert — does NOT trigger sepsis bundle (Phase 27 Step 4)
|
||||
return true;
|
||||
}
|
||||
|
||||
private static string BuildDetails(int activeCount, RedisValue[] values)
|
||||
private static string BuildActiveCriteriaList(RedisValue[] values)
|
||||
{
|
||||
var activeParts = new List<string>();
|
||||
for (var i = 0; i < QsofaCalculator.QsofaCodes.Count; i++)
|
||||
@@ -192,7 +178,6 @@ public class QsofaDetector
|
||||
if (values[i].HasValue)
|
||||
activeParts.Add($"{QsofaCalculator.QsofaCodes[i]}={values[i]}");
|
||||
}
|
||||
|
||||
return $"qSOFA score {activeCount}/3: {string.Join(", ", activeParts)}";
|
||||
return string.Join(", ", activeParts);
|
||||
}
|
||||
}
|
||||
}
|
||||
@@ -12,6 +12,14 @@ public class SepsisAlertHandler
|
||||
public async Task OnSepsisAlertCreatedAsync(
|
||||
Guid encounterId, Guid alertId, AlertType alertType, CancellationToken ct)
|
||||
{
|
||||
if (alertType != AlertType.SofaSepsis)
|
||||
{
|
||||
_logger.LogDebug(
|
||||
"Alert type {AlertType} does not trigger sepsis bundle — skipping",
|
||||
alertType.ToDbString());
|
||||
return;
|
||||
}
|
||||
|
||||
var bundle = await _bundleService.TryCreateBundleAsync(encounterId, alertId, alertType, ct);
|
||||
|
||||
if (bundle is not null)
|
||||
@@ -19,4 +27,4 @@ public class SepsisAlertHandler
|
||||
"Sepsis bundle {BundleId} created for encounter {EncounterId} (trigger={AlertType})",
|
||||
bundle.Id, encounterId, alertType.ToDbString());
|
||||
}
|
||||
}
|
||||
}
|
||||
@@ -1,177 +0,0 @@
|
||||
using System.Text.Json;
|
||||
using Microsoft.EntityFrameworkCore;
|
||||
using Serilog.Context;
|
||||
using StackExchange.Redis;
|
||||
|
||||
public class SirsDetector
|
||||
{
|
||||
// 30 minutes in seconds. This is a clinical parameter: SIRS criteria evaluated
|
||||
// outside a 30-minute window are clinically stale. The TTL enforces the window
|
||||
// automatically — no cleanup job required.
|
||||
private const int SirsTtlSeconds = 1800;
|
||||
|
||||
private readonly IConnectionMultiplexer _redis;
|
||||
private readonly IServiceProvider _services;
|
||||
private readonly ILogger<SirsDetector> _logger;
|
||||
private readonly ClinicalMetrics _metrics;
|
||||
|
||||
public SirsDetector(
|
||||
IConnectionMultiplexer redis,
|
||||
IServiceProvider services,
|
||||
ILogger<SirsDetector> logger,
|
||||
ClinicalMetrics metrics)
|
||||
{
|
||||
_redis = redis;
|
||||
_services = services;
|
||||
_logger = logger;
|
||||
_metrics = metrics;
|
||||
}
|
||||
|
||||
public async Task<SirsResult> ProcessObservationAsync(
|
||||
Guid encounterId,
|
||||
Guid patientId,
|
||||
string observationCode,
|
||||
decimal value,
|
||||
CancellationToken ct = default)
|
||||
{
|
||||
// Fast exit for non-SIRS codes. The sepsis engine subscribes to the full
|
||||
// observation.recorded stream — the majority of messages (SpO2, potassium, glucose)
|
||||
// are not SIRS-relevant and are discarded here without touching Redis or PostgreSQL.
|
||||
if (!SirsEvaluator.SirsCodes.Contains(observationCode))
|
||||
return SirsResult.NotSirsCode;
|
||||
|
||||
var cache = _redis.GetDatabase();
|
||||
var key = SirsEvaluator.CriterionKey(encounterId, observationCode);
|
||||
|
||||
if (SirsEvaluator.MeetsCriterion(observationCode, value))
|
||||
{
|
||||
// SET with EX refreshes the TTL on every qualifying observation.
|
||||
// A patient with tachycardia posting a reading every 60 seconds will keep
|
||||
// sirs:{id}:HEART_RATE alive for 30 minutes after the LAST qualifying reading,
|
||||
// not the first — the window slides forward with each new abnormal value.
|
||||
await cache.StringSetAsync(key, "1", TimeSpan.FromSeconds(SirsTtlSeconds));
|
||||
|
||||
_logger.LogDebug("SIRS criterion set: {Key} (TTL={Ttl}s)", key, SirsTtlSeconds);
|
||||
}
|
||||
else
|
||||
{
|
||||
// Criterion no longer met — remove the key immediately rather than waiting
|
||||
// for TTL expiry. If a patient's temperature normalises at 37.0 °C, the
|
||||
// fever criterion must stop contributing to the count right away.
|
||||
// Without this DEL, a recovered criterion could persist for up to 30 minutes
|
||||
// and falsely sustain a SEPSIS_WARNING count.
|
||||
await cache.KeyDeleteAsync(key);
|
||||
|
||||
_logger.LogDebug("SIRS criterion cleared: {Key}", key);
|
||||
}
|
||||
|
||||
// Count active criteria in one MGET round-trip.
|
||||
// MGET is O(N) where N = number of keys requested (4 here, always).
|
||||
// Never use KEYS pattern for this check: KEYS scans the entire keyspace
|
||||
// and blocks all other Redis operations until the scan completes.
|
||||
var allKeys = SirsEvaluator.AllCriterionKeys(encounterId);
|
||||
var values = await cache.StringGetAsync(allKeys);
|
||||
var activeCount = values.Count(v => v.HasValue);
|
||||
|
||||
_logger.LogDebug(
|
||||
"SIRS state for encounter {Id}: {Active}/4 criteria active after {Code}={Value}",
|
||||
encounterId, activeCount, observationCode, value);
|
||||
|
||||
if (activeCount < 2)
|
||||
return SirsResult.InsufficientCriteria(activeCount);
|
||||
|
||||
// Two or more criteria are active — attempt to create the alert.
|
||||
var created = await TryCreateAlertAsync(encounterId, patientId, activeCount, ct);
|
||||
return created ? SirsResult.AlertCreated : SirsResult.AlertAlreadyOpen;
|
||||
}
|
||||
|
||||
// Creates the SEPSIS_WARNING alert and its outbox event in one atomic transaction.
|
||||
// The INSERT WHERE NOT EXISTS pattern makes this safe under at-least-once delivery:
|
||||
// if the consumer crashes after the INSERT but before committing the Kafka offset,
|
||||
// the observation is reprocessed on restart. The second run hits the WHERE NOT EXISTS
|
||||
// subquery, finds the existing open alert, inserts 0 rows, and returns false — no
|
||||
// duplicate alert, no duplicate outbox event.
|
||||
private async Task<bool> TryCreateAlertAsync(
|
||||
Guid encounterId,
|
||||
Guid patientId,
|
||||
int activeCount,
|
||||
CancellationToken ct)
|
||||
{
|
||||
using var scope = _services.CreateScope();
|
||||
var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
|
||||
|
||||
await using var tx = await db.Database.BeginTransactionAsync(ct);
|
||||
|
||||
var alertId = Guid.NewGuid();
|
||||
var triggeredAt = DateTimeOffset.UtcNow;
|
||||
var details =
|
||||
$"SIRS criteria met: {activeCount} of 4 criteria active within the 30-minute window.";
|
||||
|
||||
// One SQL round-trip: check + insert atomically.
|
||||
// status IN ('OPEN', 'ESCALATED') prevents re-creating an alert that has been
|
||||
// escalated but not yet resolved — the patient is still in danger.
|
||||
var affected = await db.Database.ExecuteSqlInterpolatedAsync($"""
|
||||
INSERT INTO clinical_alerts
|
||||
(id, encounter_id, patient_id, alert_type, severity, details, status, triggered_at)
|
||||
SELECT {alertId}, {encounterId}, {patientId},
|
||||
'SEPSIS_WARNING', 'CRITICAL', {details}, 'OPEN', {triggeredAt}
|
||||
WHERE NOT EXISTS (
|
||||
SELECT 1 FROM clinical_alerts
|
||||
WHERE encounter_id = {encounterId}
|
||||
AND alert_type = 'SEPSIS_WARNING'
|
||||
AND status IN ('OPEN', 'ESCALATED')
|
||||
)
|
||||
""", ct);
|
||||
|
||||
if (affected == 0)
|
||||
{
|
||||
await tx.RollbackAsync(ct);
|
||||
_logger.LogDebug(
|
||||
"SEPSIS_WARNING already open for encounter {Id} — no new alert", encounterId);
|
||||
return false;
|
||||
}
|
||||
|
||||
// Alert was created — write the outbox event in the same transaction.
|
||||
// The relay (Phase 3) will publish to alert.generated, which Phase 6's
|
||||
// notification worker reads to page the attending physician via RabbitMQ.
|
||||
db.OutboxEvents.Add(new OutboxEvent
|
||||
{
|
||||
Id = Guid.NewGuid(),
|
||||
Topic = "alert.generated",
|
||||
Payload = JsonSerializer.Serialize(new
|
||||
{
|
||||
alertId,
|
||||
encounterId,
|
||||
patientId,
|
||||
alertType = AlertType.SepsisWarning.ToDbString(),
|
||||
severity = "Critical",
|
||||
details,
|
||||
triggeredAt,
|
||||
partitionKey = encounterId.ToString()
|
||||
}),
|
||||
PartitionKey = encounterId.ToString(),
|
||||
CreatedAt = DateTimeOffset.UtcNow
|
||||
});
|
||||
|
||||
await db.SaveChangesAsync(ct);
|
||||
await tx.CommitAsync(ct);
|
||||
|
||||
_metrics.SirsDetectionsTotal.Inc();
|
||||
_metrics.ClinicalAlertsTotal
|
||||
.WithLabels(AlertType.SepsisWarning.ToDbString(), AlertSeverity.Critical.ToDbString())
|
||||
.Inc();
|
||||
|
||||
using (LogContext.PushProperty("EncounterId", encounterId))
|
||||
using (LogContext.PushProperty("PatientId", patientId))
|
||||
{
|
||||
_logger.LogWarning(
|
||||
"SEPSIS_WARNING created. ActiveCriteriaCount={Count} AlertId={AlertId}",
|
||||
activeCount, alertId);
|
||||
}
|
||||
|
||||
var handler = scope.ServiceProvider.GetRequiredService<SepsisAlertHandler>();
|
||||
await handler.OnSepsisAlertCreatedAsync(encounterId, alertId, AlertType.SepsisWarning, ct);
|
||||
|
||||
return true;
|
||||
}
|
||||
}
|
||||
@@ -1,38 +0,0 @@
|
||||
using StackExchange.Redis;
|
||||
|
||||
public static class SirsEvaluator
|
||||
{
|
||||
// The four SIRS codes defined by this project's simplified SIRS criteria.
|
||||
// Observations for any other code are ignored by the sepsis engine entirely —
|
||||
// they pass through to the outbox and Elasticsearch but do not affect SIRS state.
|
||||
public static readonly IReadOnlySet<string> SirsCodes =
|
||||
new HashSet<string> { "TEMP_C", "HEART_RATE", "RESP_RATE", "WBC_K_UL" };
|
||||
|
||||
// Returns true if the observation value meets the SIRS criterion for its code.
|
||||
// These thresholds are clinical parameters, not configuration — changing them
|
||||
// requires clinical review, not a config file edit. They live here as named constants.
|
||||
public static bool MeetsCriterion(string observationCode, decimal value) =>
|
||||
observationCode switch
|
||||
{
|
||||
// Fever (> 38.3 °C) or hypothermia (< 36.0 °C)
|
||||
"TEMP_C" => value > 38.3m || value < 36.0m,
|
||||
// Tachycardia
|
||||
"HEART_RATE" => value > 90m,
|
||||
// Tachypnea
|
||||
"RESP_RATE" => value > 20m,
|
||||
// Leukocytosis or leukopenia
|
||||
"WBC_K_UL" => value > 12.0m || value < 4.0m,
|
||||
_ => false
|
||||
};
|
||||
|
||||
// Redis key for one SIRS criterion for one encounter.
|
||||
public static string CriterionKey(Guid encounterId, string code) =>
|
||||
$"sirs:{encounterId}:{code}";
|
||||
|
||||
// All four Redis keys for one encounter — used in MGET to count active criteria.
|
||||
// The order is stable so the MGET result array always maps to the same codes.
|
||||
public static RedisKey[] AllCriterionKeys(Guid encounterId) =>
|
||||
SirsCodes
|
||||
.Select(code => (RedisKey)CriterionKey(encounterId, code))
|
||||
.ToArray();
|
||||
}
|
||||
@@ -17,6 +17,10 @@ public class SepsisBundleService : ISepsisBundleService
|
||||
public async Task<SepsisBundle?> TryCreateBundleAsync(
|
||||
Guid encounterId, Guid triggeringAlertId, AlertType alertType, CancellationToken ct = default)
|
||||
{
|
||||
if (alertType != AlertType.SofaSepsis)
|
||||
throw new InvalidOperationException(
|
||||
$"Sepsis bundle can only be triggered by SOFA_SEPSIS, not {alertType.ToDbString()}.");
|
||||
|
||||
var exists = await _db.SepsisBundles
|
||||
.AnyAsync(b => b.EncounterId == encounterId
|
||||
&& b.ComplianceStatus == SepsisBundleComplianceStatus.InProgress, ct);
|
||||
|
||||
@@ -276,6 +276,8 @@ public class SofaDetector
|
||||
return false;
|
||||
}
|
||||
|
||||
AlertCreationGuard.EnsureAllowed(alertType);
|
||||
|
||||
using var scope = _services.CreateScope();
|
||||
var db = scope.ServiceProvider.GetRequiredService<AppDbContext>();
|
||||
|
||||
@@ -332,6 +334,12 @@ public class SofaDetector
|
||||
await db.SaveChangesAsync(ct);
|
||||
await tx.CommitAsync(ct);
|
||||
|
||||
if (alertType == AlertType.SofaSepsis)
|
||||
{
|
||||
var handler = _services.GetRequiredService<SepsisAlertHandler>();
|
||||
await handler.OnSepsisAlertCreatedAsync(encounterId, alertId, alertType, ct);
|
||||
}
|
||||
|
||||
_metrics.ClinicalAlertsTotal
|
||||
.WithLabels(alertType.ToDbString(), severity.ToDbString()).Inc();
|
||||
|
||||
|
||||
Reference in New Issue
Block a user