feature: Simulator Scenarios + Clinical Validation: SOFA/GCS
This commit is contained in:
@@ -2,7 +2,7 @@
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"scenario": {
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"id": "uti-sepsis-elderly-01",
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"name": "UTI Progressing to Sepsis in Elderly Patient",
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"description": "72-year-old female presenting with UTI symptoms who deteriorates into sepsis over 4 hours, triggering SIRS, qSOFA, and NEWS2 alerts with sepsis bundle compliance.",
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"description": "72-year-old female with UTI progressing to sepsis over 4 hours. qSOFA screen fires first; SOFA delta \u2265 2 triggers sepsis bundle. NEWS2 and bundle compliance still exercised.",
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"durationMinutes": 240,
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"tags": [
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"sepsis",
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@@ -98,6 +98,36 @@
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"source": "Manual"
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}
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},
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{
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"offsetMinutes": 0,
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"type": "observation",
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"data": {
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"code": "GCS_EYE",
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"value": 4,
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"unit": "score",
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"source": "Manual"
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}
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},
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{
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"offsetMinutes": 0,
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"type": "observation",
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"data": {
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"code": "GCS_VERBAL",
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"value": 4,
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"unit": "score",
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"source": "Manual"
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}
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},
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{
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"offsetMinutes": 0,
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"type": "observation",
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"data": {
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"code": "GCS_MOTOR",
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"value": 6,
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"unit": "score",
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"source": "Manual"
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}
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},
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{
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"offsetMinutes": 20,
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"type": "observation",
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@@ -281,6 +311,56 @@
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"source": "Lab"
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}
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},
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{
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"offsetMinutes": 45,
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"type": "observation",
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"data": {
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"code": "PAO2_MMHG",
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"value": 92,
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"unit": "mmHg",
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"source": "Lab"
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}
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},
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{
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"offsetMinutes": 45,
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"type": "observation",
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"data": {
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"code": "FIO2_PCT",
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"value": 28,
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"unit": "%",
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"source": "Manual"
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}
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},
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{
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"offsetMinutes": 45,
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"type": "observation",
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"data": {
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"code": "PLATELET_K_UL",
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"value": 210,
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"unit": "k/\u00b5L",
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"source": "Lab"
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}
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},
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{
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"offsetMinutes": 45,
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"type": "observation",
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"data": {
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"code": "BILIRUBIN_MG_DL",
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"value": 0.7,
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"unit": "mg/dL",
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"source": "Lab"
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}
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},
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{
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"offsetMinutes": 45,
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"type": "observation",
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"data": {
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"code": "CREATININE_MG_DL",
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"value": 1.0,
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"unit": "mg/dL",
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"source": "Lab"
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}
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},
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{
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"offsetMinutes": 40,
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"type": "order",
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@@ -450,7 +530,7 @@
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"unit": "bpm",
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"source": "Device"
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},
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"note": "SIRS criteria met: Temp >38.3 + HR >90 \u2192 SEPSIS_WARNING"
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"note": "Temp >38.3 + HR >90 \u2014 early sepsis physiology"
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},
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{
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"offsetMinutes": 90,
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@@ -627,7 +707,7 @@
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"unit": "bpm",
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"source": "Device"
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},
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"note": "NEWS2 = 6, SIRS 3 of 4 criteria met (Temp, HR, RR)"
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"note": "NEWS2 = 6, continued deterioration"
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},
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{
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"offsetMinutes": 120,
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@@ -698,7 +778,7 @@
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"unit": "\u00d710\u00b3/\u00b5L",
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"source": "Lab"
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},
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"note": "Repeat labs \u2014 WBC elevated, lactate rising, SIRS 4/4"
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"note": "Repeat labs \u2014 WBC elevated, lactate rising"
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},
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{
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"offsetMinutes": 120,
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@@ -730,6 +810,48 @@
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"source": "Lab"
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}
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},
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{
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"offsetMinutes": 125,
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"type": "observation",
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"data": {
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"code": "PAO2_MMHG",
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"value": 68,
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"unit": "mmHg",
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"source": "Lab"
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},
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"note": "Worsening gas exchange \u2014 SOFA Resp \u2191"
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},
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{
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"offsetMinutes": 125,
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"type": "observation",
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"data": {
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"code": "FIO2_PCT",
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"value": 40,
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"unit": "%",
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"source": "Manual"
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}
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},
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{
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"offsetMinutes": 125,
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"type": "observation",
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"data": {
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"code": "PLATELET_K_UL",
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"value": 95,
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"unit": "k/\u00b5L",
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"source": "Lab"
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}
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},
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{
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"offsetMinutes": 125,
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"type": "observation",
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"data": {
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"code": "CREATININE_MG_DL",
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"value": 2.1,
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"unit": "mg/dL",
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"source": "Lab"
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},
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"note": "AKI \u2014 SOFA Renal \u2191; delta \u2265 2 \u2192 SOFA_SEPSIS"
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},
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{
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"offsetMinutes": 125,
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"type": "medication",
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@@ -1308,46 +1430,34 @@
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"description": "HR enters warning range (91 bpm)"
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},
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{
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"afterOffsetMinutes": 90,
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"afterOffsetMinutes": 105,
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"type": "alert",
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"alertType": "SEPSIS_WARNING",
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"description": "SIRS criteria met: Temp 38.4\u00b0C (>38.3) + HR 96 (>90) = 2 of 4"
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"alertType": "QSOFA_SCREEN",
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"description": "qSOFA \u2265 2 \u2014 screen positive, recommend SOFA labs"
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},
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{
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"afterOffsetMinutes": 90,
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"afterOffsetMinutes": 125,
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"type": "alert",
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"alertType": "SOFA_SEPSIS",
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"description": "SOFA delta \u2265 2 from baseline after repeat labs"
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},
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{
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"afterOffsetMinutes": 125,
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"type": "bundle",
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"description": "Sepsis bundle auto-created with 4 orders: blood cultures, serum lactate, broad-spectrum antibiotics, IV fluid resuscitation"
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"description": "Sepsis bundle auto-created; triggeringAlertType = SOFA_SEPSIS"
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},
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{
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"afterOffsetMinutes": 105,
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"type": "score",
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"scoreType": "NEWS2",
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"expectedMinimum": 5,
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"description": "NEWS2 reaches 5 (HR=1, RR=2, Temp=1, SpO2=1) \u2192 WARNING threshold"
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"description": "NEWS2 reaches medium risk"
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},
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{
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"afterOffsetMinutes": 135,
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"type": "alert",
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"alertType": "NEWS2_EMERGENCY",
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"description": "NEWS2 reaches 8 (HR=2, RR=2, SBP=1, Temp=2, SpO2=1) \u22657 \u2192 EMERGENCY"
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},
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{
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"afterOffsetMinutes": 135,
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"type": "score",
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"scoreType": "NEWS2",
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"expectedMinimum": 7,
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"description": "NEWS2 \u22657 sustained through peak deterioration"
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},
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{
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"afterOffsetMinutes": 150,
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"type": "alert",
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"alertType": "QSOFA_WARNING",
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"description": "qSOFA 3/3: RR 24 (\u226522) + SBP 98 (\u2264100) + AVPU 1 (\u22651)"
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},
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{
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"afterOffsetMinutes": 130,
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"type": "bundle",
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"description": "Sepsis bundle COMPLIANT \u2014 all 4 orders completed within 40 minutes (blood cultures T+92, lactate T+95, ceftriaxone T+125, IV fluids T+130)"
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"description": "NEWS2 \u2265 7 at peak deterioration"
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}
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]
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}
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